J Gynecol 2017, 2(3): 000144

Recurrent Pregnancy loss is defined as three or more consecutive pregnancy losses before 20 wks gestation. Usually causes are found in 70-80% of cases as chromosomal, anatomical defects, thrombophilias-both acquired and inherited, endocrine. But in 20-30% no definite cause is found. We searched electronic databases Pubmed from 1950-2016 using different keywords. As for the diagnosis, management remains controversial. Here we review the basis of use of various kinds of therapies like progesterone, low molecular weight heparin, aspirin, intravenous immunoglobulin, intra lipid therapy and steroids for routine use in RPL and is empiric use of these agents justified.